I came to this book via an excellent podcast, Maintenance Phase, which referenced it extensively for one of their episodes. As I have listened to all their episodes, I can’t remember which one, but it does stand in for their ethos generally – that ethos being that any measure of food intake and energy output is contingent at best, and everything we have isn’t great, it’s just better than nothing. Which is mainly about the BMI scale and the Atwater values.
Interesting facts and observations:
‘Packages began to sport claims that their contents were free of fat, cholesterol, trans fat, salt, or sugar; contained vitamins or antioxidants; or were organic or could help prevent heart disease or immune disorders. Because people tend to interpret the meaning of such claims as “low calorie,” health claims are calorie distracters.’
‘The calorie, [Nick Cullather] says, “has never been a neutral objective measure of the contents of the dinner plate. From the first its purpose was to render food and the eating habits of populations politically legible.”
How calories are actually measured (wild):
‘You place a weighed portion of food in the bomb (a sealed chamber), which has been filled with pure oxygen under high pressure. After immersing the bomb in a measured quantity of water, you ignite the food and let it burn (oxidize) to completion. The heat released by the burning warms the surrounding water. You calculate the calories from the measured rise in water temperature. Calibrated appropriately, bomb calorimeters can give quite accurate measurements of the number of calories in a food.’
‘Unless you engage in a great deal of physical activity, basal metabolism is likely to account for about two- thirds of your total calorie needs.’
Why measures don’t focus on exercise:
‘Moving more does not affect the economic interests of food companies or any other powerful industry.’
Like the people who make Fitbits.
‘fidgeting— has been found to account for an impressive 100 to 800 calories a day’
‘Doubly labeled water experiments show that both the BMR and the total energy expenditure (including physical activity) increase with increasing overweight or obesity. Despite the relatively lower energy cost of maintaining body fat, heavier bodies take more energy to maintain and to move. The increase in basal and total expenditure with weight appears to hold true at any level of physical activity.’
‘we consider finding out what people eat the greatest intellectual challenge in the field of nutrition today. Why? We have no nice way of saying this. Whether consciously or unconsciously, most people cannot or do not give accurate information about what they eat. When it comes to dietary intake, pretty much everyone forgets or dissembles. This problem makes surveys of dietary intake exceedingly difficult to conduct and to interpret.’
Having done an MPH, I can only agree.
Why a single-drug target will never work:
‘Getting glucose to the brain is so critical that it is the regulatory system's first priority. To protect brain fuel supplies, the system evolved to be highly redundant. If one signaling factor fails to function, another quickly compensates. And because some signaling factors have multiple effects, drugs aimed at one function may also cause undesirable effects on others.’
‘Attractive as it is, the idea of thrifty genes is not universally accepted. If such genes were so important for the survival of ancient humans, then everyone living in modern- day “eat more” food environments ought to be obese. John Speakman, a biologist from Aberdeen, views obesity in modern society more as a matter of “genetic drift.”’
‘In such environments, matters largely beyond personal control— the presence of other people, the location of meals, how often meals appear, how large food portions might be, how tasty the foods are, and how they are advertised— are remarkably effective at overcoming physiological regulatory mechanisms.’
Environment, environment, environment.
‘Reversing this level of calorie imbalance will be difficult for most people to manage. They cannot do it alone. As Katan and Ludwig suggest, “Rather, an effective public health approach to obesity prevention will require fundamental changes in the food supply and the social infrastructure. Changes of this nature depend on more stringent regulation of the food industry, agricultural policy informed by public health, and investments by government in the social environment to promote physical activity.” We think so too.’
‘In 2009 the value of the diet industries in the United States was estimated at nearly $ 60 billion,’
‘Even today [Lulu Hunt Peters’] advice sounds remarkably familiar: “You may eat just what you like— candy, pie, cake, fat meat, butter cream— but— count your calories. You can't have many nor large helpings, you see; but isn't it comforting to know that you can eat these things? Maybe some meal you would rather have a 350- calorie piece of luscious pie, with a delicious 150- calorie tablespoonful of whipped cream on it, than all the succulent vegetables Luther Burbank could grow in California…. Now that you know you can have the things you like, proceed to make your menus containing very little of them.”’
‘In its massive review of studies of diet and weight loss, the 2010 Dietary Guidelines Advisory Committee concluded, “No optimal macronutrient [protein, fat, carbohydrate] proportion was identified for enhancing weight loss or weight maintenance. However, decreasing caloric intake led to increased weight loss and improved weight maintenance…. Diets that are less than 45 percent carbohydrate or more than 35 percent protein are difficult to adhere to, are not more effective than other calorie- controlled diets for weight loss and weight maintenance, and may pose health risk, and are therefore not recommended for weight loss or maintenance.”’
The history of American obesity:
‘In 1973 and 1977, Congress passed laws that reversed long- standing farm policies aimed at protecting prices by controlling production. These policies paid farmers to set aside acres, but that changed when Earl Butz, a former dean of agriculture at Purdue, became USDA secretary and reportedly urged them to plant “fencerow to fencerow.” Whether Butz really said this or not— no source has ever been found for the statement— the new policies encouraged farmers to plant as much as they possibly could. Food production increased, and so did calories in the food supply. The addition of 700 calories a day per capita made the food industry even more competitive. Food companies now had to find new ways to sell products in an environment that offered a vast excess of calories over the needs of the population.’
‘We like to ask the question “When did it become acceptable to eat in bookstores?” Today snack foods are sold in 96 percent of pharmacies, 94 percent of gasoline stations, 22 percent of furniture stores, and 16 percent of apparel stores. Research shows that if food is at hand, people will eat it.’
‘The Consumer Price Index indicates an increase of about 40 percent in the relative cost of fruits and vegetables since the early 1980s, whereas the indexed price of desserts, snack foods, and sodas has declined by 20 to 30 percent. Lower prices encourage people to eat more. Higher prices discourage food purchases. 21 For example, as part of its contribution to obesity prevention, Coca- Cola now offers drinks in 7.5- ounce cans but prices them higher than 12- ounce sodas. As a retailing executive once explained to us, if customers want smaller portions, they ought to be willing to pay for them.’
‘As for efficacy: one clinical trial gave orlistat to obese patients with type 2 diabetes. After four years, 52 percent of the patients taking orlistat— and eating a reduced- calorie diet— completed the study and maintained an average weight loss of 7 percent. But only 34 percent of people taking a placebo completed the study; they had an average 4 percent weight loss after four years. 11 The 3 percent difference is either impressive or not, depending on how desperate you are. And you still need to eat a reduced- calorie diet to achieve weight loss. But because almost any weight loss is associated with improved glucose tolerance, obesity specialists consider orlistat an effective treatment.’
Same goes for those bloody SGLT2 inhibitors.