Early Phase Drug Evaluation in Man

by John O'Grady, Otto I. Linet

Early Phase Drug Evaluation in Man is a comprehensive, practical guide that covers pre-clinical information relevant to early human studies, including pharmaceutical, metabolic, toxicological, and regulatory aspects, as well as the general considerations relevant to all early human studies. Each major therapeutic area is considered by class of activity of drug. The chapters describe what measurements of drug activity are available in healthy human subjects and in patients, how to make the measurements, their value and their limitations. The contributors have been drawn internationally from the pharmaceutical industry and academia. Early Phase Drug Evaluation in Man will provide an important reference guide for industry and academic professionals involved in the development of new drugs.

737 pages, Hardcover

First published January 1, 1990

About the author

John O'Grady did not set out to be a writer. A pharmacist and founder of the Sydney Repetory Theatre, he occasionally wrote one-act plays for its benefit. After mocking his brother Frank's historical fiction, John accepted a bet that he could write a book and get it published. They're a Weird Mob was surprisingly successful, the first of his 18 books to be published.