The book can be summed up simply: great art, underwhelming story. The plot is supposed to be about the birth of a new Marvel Universe and features the declared end of both the Marvel and Ultimate universes. What we get at the end is weak, and more cosmetic changes to fill company goals rather than Crisis on Infinite Earths style reboot.
More importantly, the story we're given has some cool concepts but is often lifeless and illogical. It wasn't unpleasant or a chore to read, but at the end of the day, it was disappointing.