Steven W. Hackel
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“Some 310,000 Indians lived within the boundaries of the present state in 1769. Approximately 60,000 lived in the coastal region between San Diego and San Francisco where Serra hoped to establish a series of missions.84 The Luiseño and then the Acjachemen resided to the immediate north of the Kumeyaay. The Gabrielino occupied the coastal plain of Los Angeles, the Chumash inhabited an expanse from Malibu to San Luis Obispo, the Yokuts lived in the Central Valley, and the Salinan and Ohlone settled the central coast between Santa Barbara and the Golden Gate. The Pomo, Coast Miwok, Wappo, Patwin, and Eastern Miwok lived in the regions immediately north and east of the San Francisco Bay Area.85 Although Alta California successfully supported a large human population, it was hardly disease-free. Even before the Spaniards arrived, a wide variety of infections were common, all of which led to high mortality”
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