While tackling subjects such as identity, politics, religion, art, and history, these autobiographical tales are written with a biting humor, placing Vowell solidly in the tradition of Mark Twain and Dorothy Parker. Vowell searches the streets of Hoboken for traces of the town's favorite son, Frank Sinatra. She goes under cover of heavy makeup in an investigation of goth culture, blasts cannonballs into a hillside on a father-daughter outing, and maps her family's haunted history on a road trip down the Trail of Tears.

Take the Cannoli is an eclectic tour of the New World, a collection of alternately hilarious and heartbreaking essays and autobiographical yarns.