I first thought this Preston book would build on and continue in the vein of The Hot Zone, etc. However, this collection of this writings is much more than that. The Panic in Level 4 title subject is in that vein, but not as impactful and explorative as the much more interesting topics of the genetic, self-destructive disorder Lesh-Nyhan syndrome and what it tells us about free will and genetic determination. Also very interesting is Preston's detailed analysis and advice on interviewing for research for non-fiction writing.