Being a big fan of both historical fiction and stories about infectious diseases this book was right up my alley. My primary complaint pertains to the language that the author used, as I was often clueless as to what many of the words meant. I am sure it is historically accurate, but it didn't add anything to the story to use antiquated language when referring to objects and places IMO.
Also, Anna was a respectable heroine but I found it frustrating that she was so courageous in many instances then at other times behaved so meekly ( i.e with her father and step mother).
Oh yeah and the abrupt turn at the end came right out of left field. I think it would have been more realistic had she settled in England.