I have always <3ed Sarah Silverman for giving edge to the name Sarah.
After reading Tina Fey's Bossypants I was amazed at how much personal information SS shared about herself... and really apprecaited her honesty which goes hand-in-hand with her humor. I think people who aren't as big of fans of Sarah S. will not have the energy to get through this book, but if you are a fan of her work (as I am of the Sarah Silverman Program and other more recent works, not so much Jesus is Magic) I am pretty sure you will appreciate this book.
Also, she is one smart woman (who didn't go to college) and she is also an interesting person, so in the autobiography sense, it is interesting and definitely not like anything else I have read. Plus she backs a lot of what people have attacked as bad humor and does it intelligently and humbly.
Sarah Silverman, I continue to <3 you (despite now knowing how much you love balls, and especially because you wet the bed til so late in life and named your book that!)