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Imaginations of Unreasonable Men: Inspiration, Vision, and Purpose in the Quest to End Malaria

3.28  ·  Rating Details  ·  53 Ratings  ·  10 Reviews
Through the story of scientists pursuing an impossible dream, a renowned social entrepreneur examines what it really takes to change the world
ebook, 320 pages
Published November 9th 2010 by PublicAffairs
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Oct 19, 2011 Lora rated it really liked it  ·  review of another edition
Recommended to Lora by: L
Very interesting. I didn't realize it would be so focused on malaria, but so far a neat peek into what has motivated the money behind malaria research and how we've approached/are approaching this problem.

I really appreciate this book for examining many sides of a "single disease" problem approach. The author talks a good deal about the few people trying to develop a malaria vaccine, but also about those addressing the problem with treatments, prevention, and most importantly money and regulati
Sharon Li
Jan 16, 2015 Sharon Li rated it it was amazing  ·  review of another edition
One of the most inspirational books I've ever read. it's not just about the quest for Malaria vaccine, but about men with the vision, determination, and imagination to make nothing impossible. It is also about a new type of social philanthropy, which aims to eliminate market gaps that often undermine social solutions. I was also pleasantly surprised at the number of female leaders/visionaries Shore mentions in his book. Finally, Shore's ending quote "we must shape our own evolution, with faith t ...more
Will DeKrey
Billy brings a fresh perspective to a seemingly intractable social problem -- the eradication of malaria. He does a good job balancing writing for a popular audience with maintaining scientific rigor. At times, though, seemed as though he fell off this tightrope, sometimes pursuing a strain of scientific investigation beyond my point of interest and sometimes dumbing down ideas that I would have loved to explore further.

At the end of the day, I think Billy's motivation was a personal quest to un
Sep 13, 2012 Judy rated it liked it  ·  review of another edition
One of the previous reviewers wrote that if you are only going to read one book about the quest for a vaccine to prevent malaria, this might not be the best choice. I couldn't truthfully attest to that, but it was enough for me to be satsfied.

As it stands today, there are no vaccines that can stop infections transmitted by parasites. This book explains that those who are normally infected with malaria are the marginalized, the mute, the vulnerable. They have no political voice and no money to f
Nov 24, 2010 Andres rated it liked it  ·  review of another edition
Shelves: medical
I was disappointed with this book but only because I had thought it would be an in-depth look at malaria and the effort to find a cure. It turns out that 5% was information about malaria and 95% was information about Steve Hoffman and the business of producing vaccines. It IS about malaria but only in the sense that everyone profiled is working to treat or eradicate malaria.

The biggest problem with the book is that the author spends too much time hero-worshipping Steve Hoffman and repeating the
Apr 16, 2013 Elena rated it it was ok  ·  review of another edition
Shelves: medicine
The thesis of this book is that it takes someone a little crazy to solve big problems. It is a health science book, wrapped in biographical hero worship. To this end, Shore tells us the tale of the scientists working to save the children of Africa through the development of a vaccine against the malarial parasite. His point is made largely by repetition and he uses of multiple examples of the same thing, scientists who are working outside the establishment because they have big ideas and won’t t ...more
Michael Griswold
Bill Shore has written an amazing book about the people seeking to do something about malaria infection in the developing world where they don't have access to the drugs like many in Western countries would. Although wrapped in the cause of malaria, the book offers more of a generalized statement about what it takes to solve the seemingly unsolveable problems of this world. It takes unreasonable men and women who beileve that good is not good enough, also it takes people who are willing to do so ...more
Feb 27, 2012 Suzanne rated it really liked it  ·  review of another edition
Interesting book on the quest to end Malaria. With the Bill Gates Foundation's attention (and money) on the issue, we are seeing an increase in attention to the problem. Shore reiterates that the failure to end malaria is a failure of imagination -- once imagined, much progress has been made toward solutions from several different perspectives. Hopefully the near future will bring one that works -- the malarone was very hard to tolerate. There must be something better!
Jul 05, 2014 Kim rated it liked it
I found both the premise and the information intriguing but the writer's organization perplexing and disjointed. The last two chapters were both exceptions to that statement and very valuable information, presenting Shore's summary analysis of "Philanthropy's Shifting Tides," his associated 6 lessons, and a call for "Moral Imagination." A worthy read.
May Khaw
If you're going to read only one book on malaria, I strongly recommend Sonia Shah's Fever, which is more complete and way more interesting.

This reads more like an extended newspaper piece that went on for far too long and I shouldn't have bothered to finish it.
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