Blood Work: A Tale of Medicine and Murder in the Scientific Revolution

Blood Work: A Tale of Medicine and Murder in the Scientific Revolution

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3.56 of 5 stars 3.56  ·  rating details  ·  686 ratings  ·  168 reviews
A sharp-eyed exposé of the deadly politics, murderous plots, and cutthroat rivalries behind the first blood transfusions in seventeenth-century Europe.

On a cold day in December 1667 the renegade physician Jean Denis transfused ten ounces of calf's blood into Antoine Mauroy, a madman. Several days and several transfusions later, Mauroy was dead and Denis was framed for murd...more
Hardcover, 304 pages
Published March 21st 2011 by W. W. Norton & Company (first published December 23rd 2010)
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Linda Leaming

This is what I loved about Blood Work: from the very beginning Holly Tucker’s sense of place and time, 17th century Paris during the Age of Enlightenment, is conveyed in absolute perfect detail and she hooks us in like a great murder mystery. At the same time, we gain information and insights into our own scientific history and a time when both amazing and horrible things were happening. Blood Work tells the story of the first blood transfusions and the subsequent scientific and political strugg...more
Carol
Blood Work: A Tale of Medicine and Murder in the Scientific Revolution is a thoroughly researched and richly illustrated early history of blood transfusions.

The writing is clear and easy to understand. I had no trouble following the history. It is written as if the author was directly telling you the story.

In the Epilogue, Holly Tucker explains why she wanted to write this book. There were two reasons but the important one to me was George W. Bush's State of the Union in 2006. He wanted a ban...more
Jammies
In one way, this book is difficult to read. It deals with some truly horrific experiments in the name of science and some truly horrific human stupidity.

In another way, this book is easy to read. The writing flows smoothly, the events narrated are fascinating and the science is explained in a way that's accessible without being dumbed down.

This book reminds me of Saving Private Ryan and Schindler's List in that I'm glad I read it, I had a definite emotional and intellectual response to it, but I...more
Elizabeth
Excellent book for those who like science with their history. I would recommend this to fans of Mary Roach or Deborah Blum, or to anyone with scientific/medical curiosity. This is far from a dry recitation of facts. Like any good historical work, it helps the reader grasp the much larger sociological picture, and does so in a witty and engaging manner.
Landon
"Blood Work: A Tale of Medicine and Murder in the Scientific Revolution" is a non-fiction piece telling the history of blood transfusions, from the first animal to animal transfusion up through a handful of human transfusions, and ending with Blood Transfusions becoming more or less banded in the late 1600 early 1700 period. It's full of interesting facts surrounding early medicine, their incorrect practices, and the reasoning behind them, as well as how they relate to what we know about modern...more
Yvonne
Blood Work: A Tale of Medicine and Murder in the Scientific Revolution by Holly Tucker is meticulously researched and retold in a way that sucks the reader right in. While the subject matter is itself very interesting, the fabulous writing by Ms. Tucker raises it to an even more impressive level. With her extensive education and experience, I feel that there is no one better to bring us this true tale of life and death than Holly Tucker.

I very much enjoyed the religion versus science debate. Wit...more
Gregg

This was a very well researched history of the early days of blood transfusion. National rivalries, political intrigue, money, ego and religion all played a roll in the race to understand blood, as the study slowly moved from alchemy and superstition to empirical science.

As it sometimes seems to happen, the science got ahead of the public's acceptance and understanding of the work. The universities and governments of England, France and later Italy waged philosophical wars over the nature of hu...more
Sue
Well-researched and intensely interesting; chock-full of details about the mysteries of blood and early transfusions around the 1600’s, comparing the advances experimented between England and France, historically foes in every way. The bibliography was fantastic.

As the author, Holly Tucker, describes it: this book “sheds light on an era that wrestled with the same questions about morality and experimentation that haunt medical science to this day.”

Expect to read about a LOT more than just blood...more
Tanya
Blood Work is a solid historical monologue, though to call it "a tale of medicine and murder" is a clear attempt to pull in readers that wouldn't normally read medical history. The "murder" part of the tale comprises a mere few pages, while the great majority of the book traces the progress in scientific understanding of blood circulation and transfusion. The author's preachy epilogue, in which she equates the proscriptions on blood transfusions to today's limits on stem-cell research, seemed se...more
Jason
A fun and fascinating history, with clear parallels to contemporary objections against science that are, unfortunately, too passionately made. It isn't that passion is bad (it is wonderful!) but it allows for political idiots to easily shut off their brains. She namechecked my political party, I guess I will shut off all reason!

There are two things in this book that are intriguing: the horrors of the 17th century, and the marvels of science. The first is the horrors. On display is all of the ign...more
Terry
Tucker looks at Jean-Baptiste Denis, a young physician anxious to make a name for himself in Paris. Transfused dogs, horses, pigs and goats before becoming the first to use humans.Denis was viewed by religious contemporaries as a dangerous renegade who jeopardized the state of human souls, paved the way for monstrous hybrid (half human/half bovine) creatures and incited divine retribution. In 1667, Denis created a sensation by twice transfusing calf’s blood into a madman, apparently curing him....more
Yune
There's nothing actually misleading about the subtitle, but I was expecting a different scope for this work, which centers around an early human blood transfusion experiment that gave rise to a murder trial. I will say that Tucker is meticulous about depicting contemporaneous societal attitudes; I'd forgotten that people back then were debating which physical body part housed the soul, and while blood was a candidate, blood transfusion had very serious implications indeed. Particularly when anim...more
Jenny Maloney
If you open up this book to the table of contents, you'll see chapter titles such as:
"The Doctor and the Madman"
"The Age of Vivisection"
"The Blood of a Beast"

And, if you're anything like me, you think: Cool.

I knew only the most preliminary bits of 17th century history before picking this book up. For example, I knew who Louis XIV, the Sun King, was...but only via the Leonardo DiCaprio movie Man in the Iron Mask (and, no, I haven't read the book). And thanks to this delightful presentation of th...more
Alicia
I think the point of this author was that when government becomes involved in scientific matters, the progress of science is severely halted. She uses this example of blood transfusions in the mid 1600's to make her point and then she likens it to the work that is being done to stem cell research today. She talks about how blood transfusions were outlawed when the king of France and his advisers became convinced that the mixing of animal blood and human blood would make abnormal chimeras -human...more
Rusty
People in the olden days were stupid. That's pretty much all I can come to grips with when I read most of these narrative history books. The gist of this book is that in the early days of the scientific revolution folks in England and France were both pursuing blood transfusions on purely intellectual interests. Could it be done? What would happen? Would goat's blood put into a man create a man that produced wool? What if you put a man's blood into a cow? Would you get a cow that wanted to debat...more
KC
Blood Work is an interesting non-fiction work that chronicles the beginning of blood transfusions in the 17th century in France and England. Scientists started experimenting in blood transfusions long before the knew anything about the composition or purpose of blood- many still did not even believe in circulation of blood throughout the body!

This book describes wonderfully, if that is the right word, the gory nature of blood work before modern practices. Bloodletting was still one of the most c...more
Stefanie
I feel like I should have liked this book more. For heaven's sake, the real D'Artagnan (and Fouquet, and Mlle. de la Valliere) make appearances! Yet I felt that the tangents were pretty wide, the experiments were too inhumane (I do not blame this on the author--she reported what happened, but what happened to a large number of dogs and other animals that served as experimental subjects was off-putting), and the murder mentioned in the title opened the book to hook the reader and then closed it w...more
Krista
Tucker asks 2 questions here:

What is the Scientific Revolution?

and

Has the Scientific Revolution left us?

She shows the SR to have been a lively, morally dubious, highly competitive, and thoroughly disgusting business, and places it alongside its political context (Louis XIV) and cultural context (the reshaping of major European cities). To do so, HT traces the story of one blood transfusion gone seemingly awry, explaining both the roots of the procedure and the charged scientific/political env...more
Amanda
Mar 22, 2011 Amanda rated it 4 of 5 stars
Shelves: won, own
Blood Work is a non-fictional account of the first blood transfusions which took place in England and France during Scientific Revolution in the 1600s. If you've ever read any historical fiction or non-fiction from this period and onwards through the 1800s, you'll notice odd medical practices like blood-letting for illnesses. Leeches, draining, and more were done to bring the body back into balance through the humors. If you've never heard of this practice, I think it's mentioned in at least one...more
Kristi Thielen
The book details the remarkable story of the beginnings of blood transfusions which took place in the 17th century.

If you are surprised to hear the idea goes back that far, it is understandable: competition between the medical communities in England and France, and the establishment's hostile response to transfusion experiments performed by a maverick physician, Jean Denis, worked to bring an abrupt end to such experiments.

It would be 150 years before work to perfect transfusions began anew; it...more
Megan
Jan 11, 2012 Megan rated it 4 of 5 stars Recommends it for: Those interested in the history of science and medicine
Recommended to Megan by: Mackenzie
Overall I enjoyed this book but at some points found it hard to follow. The book was very well researched and put together but I often got confused which person did what and if they were English or French, which was often times important. I had never really thought about the history of blood transfusions or realized how much controversy was involved in the study. This book isn't someone with a weak stomach as it goes through bloody and painful procedures of dogs going through early transfusion w...more
Tanya
This book covers political, social and scientific views of blood and blood transfusions in the seventeenth century when the first experimental blood transfusions took place. In my opinion, the book is at its best in the scientific realm, both in the way it covers the changing zeitgeist around blood, circulation, and other understandings of human anatomy and in the great descriptions of the scientific practices (ewwww). I found the politics and society descriptions less compelling, but that might...more
Catherine
Fascinating and bizarre story from the 17th century of Frenchman Jean-Baptiste Denis, who conducted some of the first blood transfusions. He experienced many setbacks, in part due to failure to comprehend that donor and recipient’s species and blood type compatibility might be important factors. Ultimately the experiments ended after the death of a recipient. But did the transfusion cause the death, or was it something else?

The rich historical context of the period is artfully integrated into th...more
Lulu
Couldn't quite get into it. An interesting subject, but a bit too bloody; and the author loses focus a bit as we're asked to follow several characters from several warring countries and academies. Something I may enjoy if I pick it up again.
Cathy
Fairly interesting look at the history of research into blood transfusion, particularly one experiment in the 1600s that effectively derailed research for almost a century and a half. It was mostly interesting and educational, and the author did a good job of putting the events into context societally, culturally and politically. However, I felt that sometimes she just added too much background information, and it seemed the book was mostly supporting information rather than the main story. If s...more
Kate
When philosopher Thomas Hobbes predicted that life in 17th-century Europe would remain “solitary, poor, nasty, brutish, and short,” he was right—about academic life, anyway. The scientific careers of physician Jean-Baptiste Denis and his contemporaries, as outlined by Holly Tucker in her 2011 book Blood Work: A Tale of Medicine and Murder in the Scientific Revolution, were marked as much as (or more than) any beggar’s biography by desperation, intrigue, and misery. The book’s subtitle is more th...more
Micki
Blood Work: A Tale of Medicine and Murder could have been a very interesting and historically significant publication had it not been tainted by Tucker’s support for embryonic stem cell research and her anti-Catholic bias. Dr. Denis, the transfusionist of the 17th century had to be stopped. He was performing unethical experiments using the blood of animals and transfusing it into humans. Yes, there was intrigue surrounding the circumstances by which Denis’ experiments were stopped. This part of...more
Rick Valles
I enjoyed reading this book about the history of blood transfusion during the 17th century. This book goes into the intense conflict between France and England; competing with each other over who is ahead in the field of science. Although his book is about blood transfusion it is primarily centered around the physician Jean-Baptiste Denis, the first individual who performed a human to animal transfusion. After the Denis' story blood transfusion is not talked about for many years, and this book i...more
Jeffrey
This was quite a fascinating pop-history exploration of early work in blood transfusion and the world in which those experiments took place. The book itself is a little schizophrenic, jumping between novelistic narrations of particular historical episodes and more straightforward discourse on culture and events of the 17th century. It also tends to follow threads of inquiry fairly far afield of the immediate topic, which initially I found somewhat distracting/confusing but then grew to love as I...more
Juno
I'm 44% of the way through this and finding my enjoyment of a truly gripping tale of murder and science distinctly hampered by the quality of the writing. Too much novelistic projecting of emotions onto the characters and disjointed. When Denis transfused lamb's blood into a 16 year old boy...what happened to the boy after the first day? How is it possible he did not die? If he did not, why not? Want more detail, more fact, more mystery building! Less speculation as to the noble ambitions of the...more
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Blood Work: A Tale of Medicine and Murder in the Scientific Revolution (Paperback)
Blood Work: A Tale of Medicine and Murder in the Scientific Revolution (ebook)
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Holly Tucker teaches at Vanderbilt University, where she holds appointments in the Center for Medicine, Health & Society and the Department of French & Italian. Her writing has appeared in the New Scientist, the Wall Street Journal, the San Francisco Chronicle, Christian Science Journal, among others. Holly is also the author of Blood Work: A Tale of Medicine & Murder in the Scientific...more
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