Chromosome 6 (Jack Stapleton & Laurie Montgomery, #3)

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Chromosome 6 (Jack Stapleton & Laurie Montgomery #3)

3.82 of 5 stars 3.82 · rating details · 6,449 ratings · 144 reviews

Behind the headlines on cloning--Dr. Robin Cook blends fact with fiction in one of his most terrifying bestsellers... Chromosome 6 is a prophetic thriller that challenges the medical ethics of genetic manipulation and cloning in the jungles of equatorial Africa, where one mistake could bridge the gap between man and ape--and forever change the genetic map of our existence....more

Paperback, 456 pages

Published April 1st 1998 by Berkley (first published January 1st 1997)

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Jun 04, 2013 Nolan rated it 3 of 5 stars

If Cook has favorite characters for me, they are Doctors Jack Stapleton and
Lori Montgomery; and, both are back in this book of medical intrigue that
will move you through the streets of New York City and into the darkest
heart of a central African jungle.

A well-known mobster's body is brought to the medical examiner's office for
autopsy, and something somewhere doesn't feel right about the case to Lori
Montgomery. She's not sure what, but she thinks something about it is
highly irregular, and despite...more

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Sep 01, 2012 Terri Lynn rated it 2 of 5 stars · review of another edition

Shelves: fiction, mystery-suspense-thrillers

I liked the parts about Jack Stapleton and Laurie Montgomery but unfortunately I was totally enraged and alternatively revolted by the storyline and the African portion of the story. If only that had not been the focus of the story!

Laurie, like way too many women, had started to pressure Jack to "talk about our relationship" which he clearly does NOT want to do and he had actually backed off from her.

Ladies, please bear with me for a moment. I am 53 and have been around the block quite a few t...more I liked the parts about Jack Stapleton and Laurie Montgomery but unfortunately I was totally enraged and alternatively revolted by the storyline and the African portion of the story. If only that had not been the focus of the story!

Laurie, like way too many women, had started to pressure Jack to "talk about our relationship" which he clearly does NOT want to do and he had actually backed off from her.

Ladies, please bear with me for a moment. I am 53 and have been around the block quite a few times and know quite a bit about men as a friend and as a lover and, of course, as a wife to my husband. Guys HATE it when you start wanting to talk about the relationship. They just want to experience it, not analyze it or dissect it or yak about it. Do yourselves and the men in your life a favor, and don't go there.

I wish Laurie could hear me but , alas, she is a fictional character and can't. Jack lost his wife and daughters years ago and is not ready to be smothered and there is some tension here yet he really does care for Laurie.

Laurie had been carried out of the morgue in a sealed pine box and abducted by some mafia types years ago and now the same guys have whacked one of their own who was turning state's evidence (he just had to go out and eat one last time) while he was surrounded by police. Laurie was eager to do the autopsy but somehow the body vanished.

This ties in with what is going on in Africa. A rather whiny nerdy scientist named Kevin is living in one of the nicest homes in the jungle that a company has set up for him in his research. For 6 years he has been messing with chromosomes and in general making a "twin" for sick people out of bonobos, a type of ape closest to humans. What happens is that when someone is seriously ill, he does a little biomedical magic and creates a bonobo "twin" so the surgeons in the jungle can take whatever organ the person needs out of the bonobo which kills it and transfers the organ into the person where it is not going to be rejected.

This costs a fortune, is NOT approved by the FDA or anyone even remotely ethical, and is done out in the jungle in Equatorial Guinea with the full approval and support of the dictator. It is supersecret. Kevin, Melanie (who works there) and a nurse Candace all realize that Kevin has apparently created an island (where the animals are kept where no one can go until they are harvested) where bonobos who have had a certain amount of human DNA inserted are becoming as the first humans were- dividing into groups, using fire, living in caves, and attacking those who come to harvest them. The problem is that those making money off of this are willing to kill to keep the secret.

Is it ethical to use humanlike creatures, to create near-humans like this who can feel, think, and are alive to steal organs from? I don't think so and Kevin is starting to think not either.

As a vegan and as an animal rescuer (including farm animals, etc) and as an animal activist, I deeply resent the idea in this book that animal activists are wackos when in fact is only human monsters who devise ways to torture, abuse, subjugate, and create weapons of mass destruction to destroy other humans and other animals.

There is a lot of mysterious worrying going on by Kevin and those he works for about the gangster who was whacked and they frantically hire someone to steal the body. It appears the gangster was the recipient of a liver from a bonobo right on the island and if this was found by Laurie, the secret would be out.

This is as far as I will take it except to say that this is possibly my least favorite Robin Cook. The two stars were for (1) Jack and (2) Laurie. (less)

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Jul 28, 2012 Daniel rated it 3 of 5 stars · review of another edition

Truth is, Cook is a pretty smart guy, problem is that he can't write very well. I like the guy, really I do, and his books (namely Contagion) are enjoyable reads, but they just become so predictable and in some ways monotonous and boring. He is an excellent craftsman on the suspenseful and intriguing moments. The whodunnit? kind of moments when you find Jack and Laurie sitting in the autopsy room, analyzing a body and trying to figure out what happened. However his suspense writing is as good as...more

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Jul 06, 2010 Arys rated it 2 of 5 stars

This book has its pros and cons.

Pros: To anyone who loves the applications of biotechnology to medical fields, and its ethical implications, this book provides a good plot personally, I feel it leaves the reader with the idea that the ethics of such research and practical genetic applications are very real.

Cons: The plot. I mean, in the beginning, I liked how the plot builds in both storylines, and I liked how the story progressed. But the whole idea that a medical examiner from New York would m...more

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Feb 12, 2011 Kitty rated it 3 of 5 stars

This was actually a re-read for me. Kevin Marshall is a molecular biologist working in Equatorial Guinea. He is able to manipulate Chromosome 6 of bonobos (ape-like creatures) and replace with human DNA. This allows for humans to create their own organ donors (bonobos) and then the organs are harvested when needed. GenSys is funding this project and they don't really appear to be evil...but their on-site managers are greedy and will do anything to keep the lucrative project going. When Kevin see...more

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Apr 16, 2012 Hollowman rated it 3 of 5 stars · review of another edition

Shelves: audiobook, ipod-mp3, kindle-read, read-in-multi-format

Hmmm ... not a bad tale and clearly written, tho' light on characterization (typical Cook). Presented science is so-so, but more trivial and incorporated to impress and dazzle under-examining readers as opposed to constructing a solid framework for a credulous story/plot.

Some may call Cook a simple, pedestrian writer ... but (and speaking for myself of course) he manages to compose/edit in a manner giving final (reader's end) prose speed and fluidity. Cook stays dynamically focused w/o getting b...more

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Aug 08, 2011 Shabbeer Hassan rated it 3 of 5 stars · review of another edition

I had always enjoyed Robin Cook's books, but then I gave up on him. His books just got so repetitive and predictable. So it's been a long time, but I decided to give Chromosome 6 a try. This book seemed a bit harder-edged than the other Cook books I'd read, with a very serious theme, and a respectful look at the relevant issues.

There are two related stories going on. One takes place in New York, where a mobster's death takes a strange turn during the autopsy. The investigators stumble onto a rea...more I had always enjoyed Robin Cook's books, but then I gave up on him. His books just got so repetitive and predictable. So it's been a long time, but I decided to give Chromosome 6 a try. This book seemed a bit harder-edged than the other Cook books I'd read, with a very serious theme, and a respectful look at the relevant issues.

There are two related stories going on. One takes place in New York, where a mobster's death takes a strange turn during the autopsy. The investigators stumble onto a real mystery: the victim had been the recipient of a liver transplant, yet there was no record of such an operation having been performed. Furthermore there is no evidence of anti-rejection medication in the man's system. Thus Jack Stapleton and Laurie Montgomery (returning characters from other Cook novels) are drawn into something that ends up being much bigger than they could possibly imagine.

The second story takes place in Africa. Researchers there have developed a chromosome transfer process whereby chimp-like animals called bonobos could have their genetic makeup altered. Extremely wealthy people can pay to have a bonobo altered in such a way so that the animal's organs would be perfect clones of their own organs. Thus they are perfect for transplants. But, something else is going on. It seems that altering the genetic code of the animals has changed them in ways most unexpected. Researcher Kevin Marshall is starting to figure out what's happened to the animals, and he's terrified.

The two stories develop independently for most of the book. The reader is usually let in on all of the secrets, even though everyone else is in the dark. Towards the end, the stories collide as the New York team heads to Africa to get to the bottom of their autopsy mystery.

For the most part, the book was very exciting. The stories develop quickly, and you never really know which way they're going to turn. There are minimal subplots, very little distraction from the two main stories. For my part, I really enjoyed the New York story. Watching Jack and Laurie work together to solve the clues was so much fun. The Africa story was a bit harder to follow, and a bit more mundane, for the most part.

I did not like how Cook handled the characters. With very little development, I didn't feel like I got to "know" them at all. And some of them were extremely annoying. Especially the two women working with Kevin in Africa. A nurse, and a genetic technician, you might expect two smart, strong women. Nope. I kept imaging two pre-teens, giggling while passing notes in school. That's basically the way these two air-heads acted. With barely one brain cell between them, and Kevin following them around like a puppy dog, it's a wonder the three them were able to accomplish anything.

But the biggest disappointment in this book is the ending. Or, lack thereof. It's as if Cook suddenly realized his time was up, so he'd better throw an ending together. There was an epilogue, but it was the most incomplete one I'd ever seen. You'd think that if you're going to bother writing an epilogue, you'd tie up all of the stories and characters. But Cook doesn't. We're left with using our imagination to decide what ultimately happened to all of the characters.

Overall, this was an exciting story that took a serious look at consequences. Consequences of research gone too far. And consequences of greed. Read it, simply because the story is a good one. But don't look for greatness - it's not here.

My Rating -- 2.5/5(less)

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Feb 19, 2013 Henri Moreaux rated it 3 of 5 stars

Shelves: business-finance, medical, mystery-suspense, americas

An odd book, in the last episode (Contagion) Dr Jack Stapleton was a cynical & sarcastic risk taker whose banter I quite enjoyed, in the opening of this book suddenly he has the appetite for risk of a 90 year old with osteoporosis, then suddenly he decides to flit off to Africa, with his own money, and 5 additional people, 2 of which were complete strangers he's just met. It all was a bit ramshackle.

On the medical side of things, the areas of the book which dealt with forensic pathology and...more

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Jul 17, 2012 Dale rated it 2 of 5 stars · review of another edition

Great idea for a story, very poor follow through.

I've read 2 or 3 Robin Cook books and Chromosome 6 will most likely be my last. To be completely truthful, I didn't read this one, I heard it as an audiobook.

The story idea is quite original - scientists are using bonobos (a chimp-like primate in West Africa) to grow hybrid human/bonobo organs for the ultra-rich. These are specifically matched to each client and held in an animal preserve until needed. Unfortunately, there may be unintended resu...more

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Jul 28, 2012 Iñaki Tofiño rated it 4 of 5 stars · review of another edition

Conforme iba avanzado tenía la extraña sensación de haber leído ya el libro y, efectivamente, después de consultar mi cuaderno de lecturas he visto que lo leí a finales del 2001. No importa, me ha gustado.
Literatura de evasión, leído con la excusa de que aparecía Guinea Ecuatorial, un país que me interesa especialmente; un best seller que mezcla mafia, medicina, Nueva York y Cogo (la antigua Puerto Iradier). Sin pretensiones, pero bien trabado.
La edición y la traducción ya son otra cosa: párrafo...more

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Apr 20, 2010 Trice rated it 1 of 5 stars Recommends it for: people who like thrillers, science, ethical questions, and who don't mind bad writing

Recommended to Trice by: Doc Aaronson

Shelves: science

yuck! I struggle to understand why Robin Cook is so popular. His writing is terrible and his characters are blank outlines and stereotypes. He did get me laughing at a couple points, but my recollection is that this was because something the characters said or did was so ridiculously bad.

I read Chromosome 6 in college for a biology senior seminar on ethics and evolution and I will say that he explores some interesting and important ethical issues, which made this book great for the purpose and i...more

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Feb 13, 2009 Melissa rated it 4 of 5 stars

Since I already knew the characters from Blindsight and Contagion (forensic pathologist Dr. Jack Stapleton and his colleague, Dr Laurie Montgomery), it was easy to get back into them, but this time we went to Equatorial Guinea, and I loved the voice of Arthur Addison reading it (unabridged book on tape). It was a little hard to follow at first, unsure of where Cook was going with the equatorial Guinea connection, but it was worth it. One thing worth mentioning is the heavy medical terminology as...more

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Jan 23, 2012 Daniel rated it 2 of 5 stars

Jack Stapelton, a medical examiner, is faced with an interesting case of a well known mobster who was gunned down. The cause of death isn't a mystery, but the fact that his liver didn't seem to belong to him, and may not have belonged to a human at all, sends Stapelton on a hunt to get to the bottom of the 'mystery liver'.

This is the first Robin Cook book that I've read. It took me a long time to read (2 months) and I can't say it was because it was particularly dense. It was because I simply di...more

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Jun 05, 2013 Jayesh Bhoot rated it 2 of 5 stars · review of another edition

The book starts off with a promising premise of a doctor worrying about his ethically horrifying invention in a darker, deserted part of Africa. Parallel to it, the two famous pathologists - Jack Stapleton and Laurie Montgomery - work on an intriguing, but almost clueless murder of a mobster. These two parallel story lines unfold neatly, intertwining the characters in the process.

Though the investigation of the two pathologists was awesome, it also faltered the pace of the story. Cook stuffed an...more The book starts off with a promising premise of a doctor worrying about his ethically horrifying invention in a darker, deserted part of Africa. Parallel to it, the two famous pathologists - Jack Stapleton and Laurie Montgomery - work on an intriguing, but almost clueless murder of a mobster. These two parallel story lines unfold neatly, intertwining the characters in the process.

Though the investigation of the two pathologists was awesome, it also faltered the pace of the story. Cook stuffed an excruciating amount of failed attempts at finding clues to further the investigation.

Kevin had the best character development. So did Jack, Laurie and Lou.

On the other hand, some characters seemed forced in the story. I tried really hard, but couldn't find a reason for Candace to exist, except to constantly agree with Melanie and act as a wonder object for the bonobos.
Also, why the hell would Warren and Natalie land themselves in the whole mess without any motivation?

However, the most infuriating character development was of Melanie. If I were Kevin, I would have shot her at some point. Her teenage-ish, stubborn 'bravery' landed her (and her buddies) on hot waters several times. But when the need arose, she cried out like a baby.

The most disappointing part, however, is the climax. It seemed like the author lost interest in the novel by the time he reached the end, and wrapped it up hastily. The protagonists seemed to breezed through Cogo, where I had expected a lot of action to happen, given the presence of the bonobos. Also, fates of a lot of characters went unexplained; to the extent where I had a feeling that the novel was missing several pages in the end. And it was an e-book.

Robin Cook's novels are always double-edged swords for me. Whenever I begin one, I am sure I will come across several gripping plot elements. Accompanying that excitement, however, is a fear that the storyline will falter somewhere for no reason at all.
I had better hopes for this novel, but it was only slightly better than my previously read disaster 'Mutation'.(less)

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May 09, 2012 Austin Mccarthy rated it 5 of 5 stars

Summary:Chromosome 6 takes place in two totally different main settings. There is a medical office in New York City, but there is also a medical research center, Gensys, in the town of Cogo, Equatorial Guinea, Africa. In this research facility, the scientist are expierimenting with the extraction of the short arm of chromosome six. After extracting the short arm of chromosome six, they would insert it into a bonobo, a ape-like creature that is like humans (DNA wise). This process is used for org...more Summary:Chromosome 6 takes place in two totally different main settings. There is a medical office in New York City, but there is also a medical research center, Gensys, in the town of Cogo, Equatorial Guinea, Africa. In this research facility, the scientist are expierimenting with the extraction of the short arm of chromosome six. After extracting the short arm of chromosome six, they would insert it into a bonobo, a ape-like creature that is like humans (DNA wise). This process is used for organ transplants (the bonobos were isolated on a island). The body will not reject the organs if there is a part of the original owner in it, in theory. This idea ends up working, but there is a huge ethnic and religion problem with this topic so it is kept in Africa and kept quiet. Although in Africa, there is still clients in America. One of these clients was Carlo Franconi. Franconi later dies, but there is a problem. The researchers realize that if the autopsy shows that there was a transplant of the liver in this patient but the test show up the same, then they may catch on to something. While this is going on, there is also another problem in Africa. On the isolated island, the bonobos were making and using fire. Kevin, one of the researchers, realizes this problem and investigates it. Little did he know that he was getting himself into a lot of trouble. Kevin believed that the short arm of chromosome 6 had human developmental traits. This would really jeopardize the company of Gensys.

Like/Dislike: I thought that this book was good because I am really starting to like the books with biology and chemistry. Robin Cook does a good job on this book because realistically this kind of things could happen in the future with the advancement in technology recently. I would recommend this book to almost anyone who is interested in future science or science in general. I would not recommend this to people who do not like biology or science because if they don't like biology they probably won't be able to follow this book.

Quote: In the middle of the book the Kevin realizes that the bonobos must have been hiding a cave. "All at once the number 37 appeared but no blinking red light. After a few moments, a prompt flashed onto the screen. It said: Animal not located...the program had indicated that seven of the bonobo doubles were unaccounted for.." This is were he realizes that the bonobos were using the cave like a shelter. I thought that this was significant because I think that this is when Kevin started to believe that the short arm of chromosome 6 really did have human developmental traits. (less)

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Aug 18, 2011 Faeleia rated it 2 of 5 stars

Ack. I thought Robin Cook should be a fantastic read, but I felt cheated when I finished it. The story took rather long with its back stories to build up. The characters were annoying for the most part and stereotypical. (I actually found Kevin to be a wuss and a meek pushover, and Melanie to be a bitch of a pain in the ass with anger for brains.. can she do nothing but have her arms akimbo in annoyance about something and demanding her way? Candace was equally useless as an airhead with no appa...more

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Jul 04, 2007 Sarah Sammis rated it 1 of 5 stars

Shelves: released

In 1896, H. G. Wells published The Island of Doctor Moreau in response to the debates over animal vivisection. A hundred and one years later, Robin Cook, updated the basic plot in Chromosome 6 to reflect recent progress in DNA research but didn't manage to bring any new insights to table.

Chromosome 6 is one of the worst books by Cook I've ever read (and perhaps one of the worst full-stop). The winner for worst book by Cook still goes t Coma which is both misogynistic and poorly written; Chromos...more

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Jul 14, 2009 Gabby-Lily Raines rated it 4 of 5 stars

Chromosome 6 presents an intriguing point of view from a storytelling front - as well as challenging whether or not a certain front of genetic manipulation should be followed.

The book is a great medical thriller and poses one of the best not only "What if?", but also "Should you if you had the wherewithal to do so?" questions.

After all, if you were able to have a perfect genetic match for any transplant you might need, would you take it? But what if it involved the kind of research that could an...more

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Dec 09, 2008 Josh rated it 3 of 5 stars

Chromosome 6 was interesting to me as I am studing the human body at school and actually understood the medical jargon in this book. This was a very smart story. Obviously, the author knows a lot about biology and it was fun to read a fictional story based on scientific facts, but I don't feel that Robin Cook is a very good story teller. The entire plot is fed to the reader about a fourth of the way through the book, which made the end anti-clamatic. I found the story line about cloning to be ve...more

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May 04, 2012 Vicki rated it 4 of 5 stars

I enjoy Robin Cook novels because they are usually filled with medical jargon but light reading - good for the beach. C6 deals with the unexpected outcomes of tampering with things only partially understood. Just because a new research procedure is do-able doesn't mean it is the wisest procedure to complete. Add a dash of deepest, darkest Africa, big NY expense accounts, and wealthy mobsters, stir well and you have the makings of an enjoyable thriller.

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Jan 22, 2011 Lauren rated it 2 of 5 stars

Shelves: action-adventure, thriller-horror-mystery

I feel like this book was very...muddled. I found myself far more fascinated by the happenings in Equatorial Guinea than in New York. It was a matter of one being unique and truly interesting, and the other one dragging on and on, and being boring.
I loved what was going in in EG. I didn't understand very much of the Microbiology lingo, but I was able to at least grasp the basic idea of it. I feel like it was much more sus
REVIEW TO BE FINISHED SOON

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Jun 16, 2013 Terrific Terry rated it 5 of 5 stars

This book is amazing Science fiction in the area of gene cloning. Bonobos serve as compatible organ donors but no plan is perfect especially with intervening forces of nature. The book educates readers on plausible flaws in light of promising Science. This book sparked y interest in Molecular Biology and influenced my choice for my undergraduate course-Biochemistry. Talk of a life transforming book

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Oct 01, 2009 Carole rated it 3 of 5 stars

A good read. Kind of scary when you think of all the gene manipulation that is being attempted these days. I had a little trouble sometimes believing that some of the characters would actually attempt some of the brave/reckless things that they did, but I guess maybe there are "ordinary" people who would do those things. Or, maybe that's why they call it fiction.

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Jul 24, 2011 Suby rated it 5 of 5 stars

A most extraordinary novel by Robin Cook. Its just not the treat of reading a fine medical thriller involving creation of authentic bio doubles for humans so that their organs can be harvested and transplanted without any fear of rejection - but plenty of adventure too is thrown in - in a possibly fictitious West African country!
I liked the book very much.

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Oct 29, 2008 Terri rated it 2 of 5 stars

Shelves: medical-thrillers

Laurie and Jack work in the NYC medical examiners office. A body disappears from the morgue and then reappears as a floater. They are determined to get to the bottom of the theft and why the body shows signs of a recent liver transplant but no signs of immunosuppresent drugs and shows odd DNA information.

Meanwhile, in Equitorial Guinea, there is a lab where primates are being genetically altered to produce donor organs specific for individuals. A lot of money is involved and keeping these secret...more

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Dec 01, 2012 Bill Thibadeau rated it 3 of 5 stars

Enjoyable read with an interesting premise. Given the way genetic research is growing, the plot is certainly plausible. This book was written 15 years ago making it even more prophetic.
The characters meshed well. There were minimal characters that were not germaine to the story.
Overall a good read - more a 3.5 star.

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Jul 28, 2009 Kelly rated it 3 of 5 stars

Shelves: fiction, medical, thriller

I like science based books that mix fact and fiction, and this book does this. I think Cook writes great medical thrillers. I read this book quickly because I found the topic enthralling. I know that the book is older now and other genetic and cloning books have been written, but I think the book is still relevant today.

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Jul 29, 2009 Ashvin rated it 1 of 5 stars

Craptastic. I think it might have been with this book that I realized that people like Robin Cook must use ghost writers as well. Not that he's a literary genius, but this sucks balls so hard that he must have accidently had a drunken frat boy write this piece of shit. You know it's a bad book when the black guy takes a trip to Africa and all he can do is stare in amazement at the "mother country"

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Jul 20, 2012 Dagny rated it 4 of 5 stars · review of another edition

Shelves: horror-sf-thriller

In this medical thriller Cook returns us to the characters who work in the NYC morgue. They share the scene with characters at a research complex on the west coast of Africa. In non-stop action, the two stories converge with a harrowing climax. I found the African part totally fascinating.

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Jul 11, 2011 Jodi rated it 4 of 5 stars · review of another edition Recommends it for: everyone!

Shelves: books-in-a-series

I have always enjoyed Robin Cook's books - something about a good medical thriller excites me! I also love the series with Laurie Montgomery and Jack Stapleton in them! I hope the possiblility of creating a "double" to use for transplants never happens in the way it happened in the book - too much worry about ethics!!!

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About Robin Cook

Librarian Note: Not to be confused with British novelist Robin Cook a pseudonym of Robert William Arthur Cook.

Dr. Robin Cook (born May 4, 1940 in New York City, New York) is an American doctor / novelist who writes about medicine and topics affecting public health.

He is best known for being the author who combined medical writing with the thriller genre of writing. Several of his books have been b...more

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Chromosome 6 (Jack Stapleton & Laurie Montgomery #3)

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