The Second Brain: A Groundbreaking New Understanding of Nervous Disorders of the Stomach and Intestine

The Second Brain: A Groundbreaking New Understanding of Nervous Disorders of the Stomach and Intestine

3.69 of 5 stars 3.69  ·  rating details  ·  74 ratings  ·  16 reviews
Dr. Michael Gershon has devoted his career to understanding the human bowel (the stomach, esophagus, small intestine, and colon). His thirty years of research have led to an extraordinary rediscovery: nerve cells in the gut that act as a brain. This "second brain" can control our gut all by itself. Our two brains -- the one in our head and the one in our bowel -- must coop...more
Paperback, 336 pages
Published November 17th 1999 by Harper Perennial (first published November 1st 1998)
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Keith Kendall
Mar 13, 2013 Keith Kendall rated it 4 of 5 stars  ·  review of another edition
Recommended to Keith by: Martha Char Love
Two months ago I didn't even know that there is such a thing an an enteric nervous system (ENS). Thanks to the Anatomy and Physiology class that I am taking, I learned that it exists. When Martha Char Love reviewed this book, I acquired a desire to learn more about the ENS.

This books starts out like a travelog written by a very engaging writer, who spices his writing with witty humor that is delightful to read. Even though it reads like a travelog, yet the writing is so engaging that I read on,...more
Katie
“Gut instinct”, “My gut tells me”, “I have butterflies in my stomach” – all the ways that we express emotions and thoughts. Our “guts” (the stomach, esophagus, small intestines, colon) are what Dr. Gershon (a neurobiologist) calls “our second brains” and chaos in one brain creates misery in the other. Consider this: 95% of the body’s serotonin is made in the bowel (serotonin being a key neurotransmitter in the regulation of mood, appetite, and sleep). Dr. Gershon also proposes that “the ugly gut...more
Nick
Gershon is a pioneer in the understanding of the gut, the colon, and all the other parts of our bodies that most of us would rather not think about. But we should: it turns out that we have more neurons in our gut -- yes, neurons, like in our brains -- than a cat has in its brain. Our tummies are, in some weird sense, smarter than cats. Gershon explores this mystery -- if the gut is thinking, what is it thinking about? -- and many others, focusing especially on the diseases of the gut and colon....more
Martha Love
If you are planning to be a student of medicine or neuro-psychology, then you seriously might start with this book. Gershon shares his 30 years of research of the gut and its enteric nervous system in a detailed story account, which is technical but very readable to the interested student. It may not be on your official prerequisite reading list given to you by the college you are about to attend, but trust me and read it anyway because it deserves to be read for its revolutionary content. Until...more
Michael Connolly
The Author
The author is not a gastroenterologist, but a neurobiologist, whose interest in the serotonin neurotransmitter took him down into the bowels of medicine. This book is a history of the development of the understanding of the intestinal nervous system, a history in which the author played a major role.

How Science is Actually Done
The author describes numerous experiments he and other conducted to figure out the intestinal nervous system. There is a great deal of information and the writi...more
Anne
Sorry Dr. John. Had to put this one down for now... But if you are interested in the enteric nervous system, check this one out.
Cindy Ratowski
A tough technical read but wonderful insights and hope for anyone suffering from any kind of functional bowel disease.
Lynn
Mar 24, 2013 Lynn marked it as to-read
Recommended by qigong master in Greenwood.
Susan
Dec 14, 2008 Susan added it
I confess, I ended up skimming quite a bit of the second half because it was due back at the library. Interesting, but I don't really have the science/medical background to find it enthralling. But know I know that I have an enteric nervous system and it produces a lot of serotonin.
Raechelle Thomas
Very interesting, but a little too technical for my pea brain; fascinating stuff, none the less. Too bad he's mainly into figuring out drugs for the ailments rather than more natural stuff. But as he sees it-natural ain't so good-and he points out e-coli and botchulism as being natural too; good point-but still....
Andy
Jun 30, 2007 Andy rated it 4 of 5 stars Recommends it for: people with digestive problems
Your gut has its own intrinsic nervous system. If you were to cut the vagus nerves (that run between the brain and the bowel), the enteric nervous system would still go on functioning from stomach to colon.

This dude knows his stuff and really breaks it all down.
Anna Macnak
Pretty hard to read. I will read this one in the future when my biochemistry is a little more concrete and see if I can get more out of it! The hardest part about reading it is the amount of time the author spends tooting his own horn.
Brittney Smith


Not what I expected. More of an account of the scientists and methods involved in studying the enteric nervous system than any practical health advice.
Julie Isen
May 02, 2010 Julie Isen is currently reading it
This book is more technical than I expected, but still pretty fascinating. Hopefully I can get through it and understand it too.
Rick
interesting book but a bit heavy for non research clinicians.
Stephanie
recommended by judi
Yazan
May 19, 2013 Yazan marked it as to-read
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May 19, 2013 Jorge is currently reading it
Shelves: nutrition
Sarah Harrell
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Shelves: science
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The Second Brain: The Scientific Basis of Gut Instinctand a groundbreaking new understanding of nervous disorders of the stomach and intestine (Hardcover)
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Chairman of the department of anatomy and cell biology at Columbia University.
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