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Resistant (Dr. Lou Welcome #3)

3.80  ·  Rating Details  ·  1,529 Ratings  ·  194 Reviews
They fight without conscience or remorse. Their only job is to kill.

They are the most ruthless enemy we have ever faced.

And they are one millionth our size.

When Dr. Lou Welcome fills in last minute for his boss at a national conference in Atlanta he brings along his best friend, Cap Duncan. But an accident turns tragic when Cap injures his leg while running. Surgeo

Hardcover, 400 pages
Published May 20th 2014 by St. Martin's Press (first published January 1st 2014)
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Popular Answered Questions

Luke Charles I was actually looking up the book on Google. Sounds believable indeed.
Daniel Palmer Hi Gary...sorry, just saw this! :) The answer is YES. Flesh eating bacteria is currently a problem and terrorists would love to get their hands on an…moreHi Gary...sorry, just saw this! :) The answer is YES. Flesh eating bacteria is currently a problem and terrorists would love to get their hands on an effective biological weapon. Here's a link to the 10 scariest bio weapons I found. Hmmm...I think the weapon in RESISTANT might be scarier. Thanks for giving the book a read. (less)

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Feb 05, 2014 Tina rated it it was amazing
Dr. Lou Welcome is a recovering drug and alcohol addict who is now an ER doc in D.C. His best friend and sponsor, Cap, is a longtime friend who has helped him through the worst times of his life. While Lou and Cap are at a medical conference in Atlanta they decide to go trail running. When Cap is hurt during the run Lou draws upon all of his medical experience to try to save him. After safely getting Cap to the hospital and on his way to recovery Lou must go back to D.C. to try to save his job. ...more
Jun 12, 2014 Diane rated it did not like it
Maybe it's my fault - I thought this would be a good summertime read, another enjoyable "end-of-the-world-as-we-know-it" apocalypse story, but I was soooo wrong. It was just cheap, political propaganda, and I resent the author's intent to vilify me as a domestic terrorist just because I sustain and support the Constitution. I was extremely disappointed in this novel.
Aug 30, 2015 Lisa rated it liked it
Shelves: medical-fiction
Having not read Michael Palmer before i saw this in the library give it a go was okay but not outstanding the story starts when a scientist working on the centres top secret case is kidnapped by terrorists Dr Lou Welcome is on the hunt that takes him from hospital wards to the top corridors of power as he races against time to stop a lethal epidemic to the world & races to save his best friend Cap who has a germ eating flesh which may kill him would read more of this author
Apr 27, 2016 Barbara rated it liked it
3.5 stars

An organization called the "Society of One Hundred Neighbors", which has exactly 100 members, wants to control the U.S government so they can get rid of policies they don't like - especially entitlement programs. The society has secret members across the country including politicians, cops, judges, doctors, scientists, business people, and so on - all of whom are dedicated to achieving their goal.

As the story opens the society has created and unleashed a 'Doomsday Germ' called Janus -
Jul 01, 2016 Esteban rated it did not like it  ·  review of another edition
First off let us get a couple of things on the table, I don't consider myself to be a high brow reader, what I look for in books is entertainment, pure and simple, anything else that comes along is surely welcome and well recieved.
With that out of the way I'd sincerely recommend anyone to avoid this book like the plague.
It starts off well enough, we are introduced to the bacteria, a very nasty piece of work that is unstoppable. This evil thing was released into the world by a group of terrorist
Ray Palen
May 01, 2014 Ray Palen rated it really liked it
It is bittersweet to have to review a novel by one of my favorite authors that was released posthumously. RESISTANT is the final novel written by the great Michael Palmer who died unexpectedly last fall

For decades, Palmer established himself as a top-notch writer of primarily medical thrillers. One of his novels even made it to the big screen as EXTREME MEASURES was made into a film starring Hugh Grant and Harrison Ford. Palmer's last few novels went away from the medical genre and were solid po
Nov 16, 2015 exncgal rated it liked it
I really did enjoy much of Michael Palmer's earlier works (he was neck-and-neck with Robin Cook for a while), and I was sorry to hear this was his last book.

That being said, the plot twists and turns (from the trail run, to the CDC, to the FBI investigation, to Red Cliffs) and the persistent amazing-ness of Dr. Lou Welcome went from pretty cool to overbearing and then just plain ridiculous. As the story went on, I started thinking of the Old Spice Guy from recent TV commercials. From Wikipedia:
Tom Tischler
Nov 07, 2014 Tom Tischler rated it it was amazing  ·  review of another edition
When Dr. Lou Welcome fills in as a last minute replacement for
his boss at a convention in Atlanta he brings along his best
friend Cap Duncan. An accident turns tragic when Cap injuries his
leg while running. Surgeons save the leg but the open wound is a
perfect breeding ground for a deadly microbial invader committed
to eating Cap alive from the inside out. The germ is resistant to
any known antibiotic and the scientist tasked with finding a cure
has been kidnapped. Turning to the Center for Disease C
Jun 01, 2014 Amy rated it liked it
As much as I enjoy Michael Palmer's novels, I am not a fan of Dr. Lou Welcome. As this book was released after Palmer's unexpected death, I wanted to like it and tried to keep a more open mind about Welcome. Truthfully, I didn't find him quite as irritating, and the premise of the medical portion of the book was interesting. The resolution was tense and shocking....all makings of a good thriller. As great a guy as "Cap" may be, I was kind of tired of reading the same descriptions of the man, and ...more
Debbie Oxier
Feb 13, 2016 Debbie Oxier rated it liked it
Normally I love Michael Palmer's books but for some reason this one fell short. I got bogged down a couple of times and found myself skipping a few pages. It wasn't the main character. I really liked Dr. Lou Welcome with all his faults and weaknesses. He had gotten hooked on amphetamines and ended up in rehab, his life in shambles. Now he's reestablished a relationship with his daughter and is getting along much better with his ex-wife. He even has a job in the medical field, helping others with ...more
Tom Duff
Aug 17, 2014 Tom Duff rated it really liked it  ·  review of another edition
Michael Palmer

I'm sad that Resistant by Michael Palmer is the last episode of Dr. Lou Welcome that I'll ever have the pleasure of reading. Palmer passed away as the book was being finished, so this will serve as his final work. I read that his family worked to finish it up and get it published, and I wonder if that's responsible for a few of the nagging issues I had with the story.

The overall story line involves the emergence of a bacteria that is resistant to all antibiotics that doct
Dr. Lou Welcome is sent to Atlanta to give a presentation for his boss. It is to take place at a medical conference where Lou's boss dreams of becoming the president. He wanted to give the talk himself but his wife's ill health forced him to remain at home.

Lou brings his best friend and AA sponsor Cap Duncan. They go running on mountain terrain and a fall lands Cap in the hospital. While there, he contracts a deadly infection for which there is no cure. This flesh eating bacteria is dubbed the D
Apr 30, 2014 Denise rated it liked it
3.5 out of 5 stars - "It is not our nature to suffer, and most of those who are offered government handouts in place of effort will take them."

My reaction to this third book in the Dr. Lou Welcome series probably was a bit affected by the fact that I had just finished watching Part I and Part II of ATLAS SHRUGGED (author: Ayn Rand) on Netflix. Both have a theme centering on political philosophy: the 100 Neighbors in RESISTANT want the government to end entitlement programs such as Social Securi
Dan Curnutt
Apr 07, 2014 Dan Curnutt rated it it was amazing
Michael Palmer gives us another Medical drama / action thriller that is amazing. He takes four or more different sub-plots about one bacterial infection and weaves them together in an unforgettable novel.

What would happen if 100 ultra rich and powerful people in the United States formed a secret society that was set on bringing our Government to it's needs and forcing it to close down all social programs, such as Social Security, Medicare, Food Stamps, etc. What would happen. Well this group com
Benjamin Thomas
Medical thrillers seem to come and go and often, after completing my reading of them, I tend to toss them aside, grateful for the opportunity to get to a really good book. I’ve even done that with a Michael Palmer book or two in the past. But I’m happy to report that this series of books featuring Dr. Lou Welcome is probably Palmer’s best work.

The plot for this novel sounds, at first glance, extremely hokey…something reminiscent of a movie-of-the-week from back in the 70’s. A group of 100 right-
May 11, 2014 Cheryl rated it liked it
It has been a few books since I have read anything by Mr. Palmer. His latest and last one sounded like a winner. I am sorry that I did not read more of his books while he was alive. This book was a good, quick read. The idea of a bacterial flesh-eating virus is scary. So scary that I was talking to my co-worker about this book and told her that if this ever happened to me that I would just want to be put out of my misery. I would not want the doctors cutting of my limbs one at a time.

So the med
Apr 30, 2014 Quinn rated it it was ok
I won this book as a First Reads giveway through Goodreads. This book had such a cool premise yet the writing brought this down to a 2 star book. There was barely any character development. Characters would pop up without an explanation of who they were for another 20 pages. There is one line in the book where it is thrown out that the guy's daughter has a cat. So????

The main character depises other doctors for not being emphathetic yet in his mind he apparently can connect with people like no
Jan 01, 2015 Valerie rated it really liked it
I was saddened to hear of Michael Palmer's death in 2013, so this is the last of his writing which will be published.

It was a pretty good thriller, involving a so-called Doomsday Virus, which was actually a bacterium since it was first treatable with antibiotics. Then the bacterium mutated, and scientists were frantically looking for something that would destroy it, since the incidence of the human cases were spreading. Unknown to the government and the doctors trying to treat patients, the bact
May 16, 2014 Perkimom rated it really liked it
What's not to love? DR. Lou Welcome is back in a medical thriller by Michael Palmer. Cancel my previous engagements.
Sarah Glenn
Aug 08, 2015 Sarah Glenn rated it really liked it
This final book of Michael Palmer's is one of his best. I've read most of his books, and he grew substantially as an author over the years. In his early books, the medical details were good (of course), but some of the side characters felt a little flat. Also, if the hero was male, there was a good chance that the girlfriend or wife would be one of the villains. Most of the plots revolved around greedy corporations. I think 'The Last Surgeon' and 'Fatal' were probably the best of the early books ...more
Scott Parsons
Jan 25, 2015 Scott Parsons rated it really liked it
Shelves: thriller, politics
When starting this review, I was disappointed to learn that Michael Palmer had died in October 2013. Although some reviewers whine that this novel was published posthumously so somebody or bodies finished it, I found it to be a thoroughly enjoyable medical/quasi-political thriller. The flesh-eating "Doomsday Germ", as the media term it, was released into some hospitals by a political organization called 100 Neighbors whose mission is to roll back what Tea Party types call "the welfare state." Th ...more
Book Addict Shaun
Aug 08, 2014 Book Addict Shaun rated it liked it
Shelves: 2014
I have this annoying habit of seeing a book and wanting it and then finding out that it is part of a series. However having never read any of the books in this series or indeed anything by the author I read this as a standalone and really enjoyed it. Upon Googling Michael Palmer he sadly passed away in October 2013 so this is his final novel (which was mostly written by him I'm led to believe and brought to fruition by his family). I'll definitely be seeking out earlier books from him to hopeful ...more
Anne Martin
Apr 17, 2015 Anne Martin rated it liked it
It reads like aRobin Cook novel or a James Patterson, I mean, one from those authors so used to writing they know all the ropes to keep you hooked and reading. The problem is that the readers slowly get to know those methods too, and as much as I loved Cook in his first books, or Patterson, I've grown tired of them. This one gave me the same feeling. I know, it was published after the author's sudden death, and maybe it was not totally finished?
I did not en joy the political add to a medical thr
Nan Williams
Jun 28, 2014 Nan Williams rated it it was ok
I've really got to stop reading books started by favorite authors who died before they finished writing the book. This is another example of a book that starts well with a plausible (well, almost plausible) premise and builds to the climax - or what should be the climax.

It's obvious where someone else took over the story and finished it so that fans of Michael Palmer would have one last book of his. The last hundred (or so) pages are totally unrealistic and filled with "supermen" with fantastic
Darren Ashley
Jan 18, 2016 Darren Ashley rated it it was ok
When Dr. Lou Welcome fills in last minute for his boss at a national conference in Atlanta he brings along his best friend, Cap Duncan. But an accident turns tragic when Cap injures his leg while running. Surgeons manage to save the leg, but the open wound is the perfect breeding ground for a deadly microbial invader committed to eating Cap alive from the inside out. Meanwhile, hundreds of miles away, a teenaged girl is fighting for her life against the same bacteria. The germ is resistant to an ...more
Susan Clark-cook
Oct 25, 2014 Susan Clark-cook rated it really liked it  ·  review of another edition
I somehow got this book sent to me by accident but since it was the type of book I enjoy I decided to go ahead and read it. I am very glad I did it was very engaging right from almost word one and I found it hard to put down. It took me only two days to finish and that was due to the fact I just couldn't wait to find out how it was going finish, as there severa; ways it could have gone.
The characters are fascinating and you find yourself rooting for them, even when it seems strange things are g
Jun 10, 2014 Natalie rated it really liked it
Michael Palmer is a great suspense writer. He has all the elements for telling a story to keep you wanting more. His knowledge of medicine (being a doctor) is one of the elements of his books that keeps you coming back. Resistant is the third book with the Lou Welcome character who the story is centered around. Lou finds himself in the middle of biological warfare when his best friend who badly injuries a leg while trail running becomes infected with a virus/strain known as the Doomsday Virus. L ...more
May 19, 2014 Kdorman rated it it was ok
Michael Palmer died in October of 2013 and so this is his 20th and final novel.

The key themes common in, particularly the Dr. Lou Welcome books of an intrepid doctor, sobriety, getting through tough times, and the importance of following an AA program are all present.

Written at the same level as most of his other books Palmer carries the reader along enough so that you keep turning pages. Is there a big thumping political agenda that might be hard for some to swallow, yes.

Do the right people sh
Dec 01, 2014 Nancy rated it really liked it
I hadn't read anything by the author before so I really didn't know what I was in for when I decided to read (i.e. listen to the audio book). I found the premise of the book to be intriguing, but a bit far-fetched. I liked the characters he created and would like to now read his other books.
Doug Branscombe
Jun 15, 2014 Doug Branscombe rated it it was amazing
Early in the book we learn of an organization, 100 Neighbors, with a stated goal of "eliminate suffocating government programs of entitlement that had brought America lurching on the brink of bankruptcy". A noble cause, but their methods are likely to be accepted by many. Enter Dr. Lou Welcome, in Atlanta for a medical conference, out on a trail run with his buddy "Cap". A nasty fall in the woods and an heroic effort to rescue and evacuate Cap save his life. Recovering from surgery he becomes in ...more
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Michael Palmer, M.D., 1942-2013, was the author of Political Suicide, Oath of Office, A Heartbeat Away, The Last Surgeon, The Second Opinion, The First Patient, The Fifth Vial, The Society, Fatal, The Patient, Miracle Cure, Critical Judgment, Silent Treatment, Natural Causes, Extreme Measures, Flashback, Side Effects, and The Sisterhood. His books have been translated into thirty-five languages.

More about Michael Palmer...

Other Books in the Series

Dr. Lou Welcome (3 books)
  • Oath of Office (Dr. Lou Welcome, #1)
  • Political Suicide (Dr. Lou Welcome, #2)

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“The only entitlement guaranteed should be the fruits of one’s own labor.” 2 likes
“Prior to their discovery in 1917, phages had been linked to miracle waters—rivers in India and other places with the power to cure diseases from leprosy to cholera. Only later did scientists, examining a naturally occurring treatment for dysentery, discover these “cures” were phages, feasting on and eradicating the disease-causing bacteria.” 0 likes
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